Actively Recruiting
The Collagen Factors of Rapid Progression of Keratoconus in Children.
Led by Zhongshan Ophthalmic Center, Sun Yat-sen University · Updated on 2024-12-09
160
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this observational study was to understand the differences in clinical features and mechanisms of keratoconus between children and adults. The main questions it aimed to answer as follows: (1) to understand the characteristics of keratoconus in Chinese children. (2) to observe corneal stromal cells at the cytological level using in vivo corneal laser confocal microscopy and explore the pathogenesis.
CONDITIONS
Official Title
The Collagen Factors of Rapid Progression of Keratoconus in Children.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with keratoconus visiting the refractive clinic
- Posterior corneal surface height greater than 16 microns by Pentacam corneal topography
- ARTAve less than 424 microns and ARTMax less than 339 microns
- Clinical non-inflammatory or traumatic corneal thinning and corneal astigmatism
- Age between 10 and 50 years old
- Agree to complete follow-up examinations on time
- Participant and guardian understand and agree to participate and sign informed consent
You will not qualify if you...
- History of wearing contact lenses in the last four weeks
- Poor fixation or inability to cooperate with examinations
- History of eye trauma or surgery, including corneal collagen cross-linking surgery
- History of other eye diseases such as corneal disease, glaucoma, retinal or choroid disease
- Severe eye diseases affecting imaging like dry eye, conjunctivitis, or pterygium
- Any systemic disease affecting eye shape or refractive tissue
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zhongshan Ophthalmic Center,Sun Yat-Sen University
Guangzhou, Guangdong, China
Actively Recruiting
Research Team
D
Dan Li, MD
CONTACT
J
Junwen Zeng, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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