Actively Recruiting
Collection of Biological Samples From Patients Treated With CAR-T Cells for Hematological Malignancies
Led by University Hospital, Montpellier · Updated on 2025-07-10
300
Participants Needed
1
Research Sites
1043 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Development of CAR-T cell against CD19 B lymphoma and Acute Lymphoblastic Leukemia leaded to 2 authorized medication: Yescarta and Kymriah. Despite impressive outcomes in 3 phase II studies, never met in relapsed or refractory diseases, half of the patients don't respond to this treatment.This can be explained by a low expansion, functional alteration or short persistence of infused cells. Determination of reasons for treatment failure is the first step for optimization of this therapeutics. This project aims to bank blood samples from a cohort of patients treated with CAR-T cell for hematological malignancies in Montpellier University Hospital. Clinical data related to samples will be collected. This samples will be used to determine factors influencing efficacy of CAR-T cells treatments.
CONDITIONS
Official Title
Collection of Biological Samples From Patients Treated With CAR-T Cells for Hematological Malignancies
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient treated by CAR-T cell at the University Hospital of Montpellier
You will not qualify if you...
- Refusal to sign consent form
- Pregnant woman
- Major protected
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Département d'hématologie clinique
Montpellier, France, 34295
Actively Recruiting
Research Team
S
Sylvain LAMURE, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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