Actively Recruiting
Collection of Blood and Tissue Samples From Patients With Primary Liver Cancer.
Led by Fondazione IRCCS Policlinico San Matteo di Pavia · Updated on 2025-04-03
53
Participants Needed
1
Research Sites
140 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The project aims to collect blood, tissue samples, and clinical data from patients with primary liver cancer (mainly hepatocellular carcinoma and intrahepatic cholangiocarcinoma) undergoing systemic therapy, surgical resection, or liver biopsy. Primary liver cancer is a growing global health challenge, with over one million cases expected by 2025 and a lack of effective treatments. The three-year study will systematically collect and store samples to support translational research for new therapies. Blood will be drawn at key points during systemic therapy, while tissue samples will be obtained from surgical resections or biopsies, provided they are not needed for diagnostics.
CONDITIONS
Official Title
Collection of Blood and Tissue Samples From Patients With Primary Liver Cancer.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Primary liver cancer (hepatocellular carcinoma or intrahepatic cholangiocarcinoma)
- Signed informed consent
- Patient eligible to start first-line systemic therapy
- Patient eligible for surgical resection
You will not qualify if you...
- Concurrent conditions with a life expectancy of less than 12 months
- Autoimmune or chronic inflammatory diseases
- Substance abuse dependency
- Other active extrahepatic malignancies or those treated within the last 3 years, except for tumors resected with curative intent and no recurrence for over 3 years, adequately treated non-melanoma skin cancers or lentigo maligna with no metastasis, adequately treated carcinoma in situ of the cervix with no recurrence, prostatic intraepithelial neoplasia with no infiltrative disease, or adequately treated non-invasive papillary urothelial tumors or carcinoma in situ
- HIV infection
- Lack of patient cooperation or failure to sign the informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fondazione IRCCS Policlinico San Matteo di Pavia
Pavia, Pavia, Italy, 27100
Actively Recruiting
Research Team
M
Mario Mondelli, MD
CONTACT
S
Stefania Mantovani, MSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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