Collection of Clinical Data and Samples for Research on Hearing, Balance, Taste, Smell, Voice, Speech, and Language Disorders

What this Trial Is About

Researchers are studying people with hearing, balance, taste, smell, voice, speech, language, and other Ear, Nose, and Throat ENT disorders to collect clinical data and specimens for research. This observational study aims to build a repository of information to support future research and to evaluate participants for possible inclusion in other clinical studies. The study is conducted by the National Institute on Deafness and Other Communication Disorders NIDCD and involves participants aged 2 years and older who have or may have these disorders. Participants will receive their usual care and treatment as determined by clinical investigators, with all tests performed being part of routine care. These may include blood or tissue sample collection, hearing and balance testing with special tools, heart and lung function tests, and imaging scans. No experimental treatments are given. Some participants with known or suspected PIEZO2-related sensory dysfunction may be invited to try optional remote taste and oral sensation tests using food-grade tannic acid solutions. During the study, participants will have their medical records reviewed and agree to let their clinical data and any collected specimens be used for research. They may remain enrolled for up to two years, with the option to continue if further care is needed. Researchers will track ongoing clinical data collection and evaluate participants for clinical study candidacy. All procedures and tests will be explained, and participants can ask questions at any time.

Collection of Clinical Data and Specimens for Research in Hearing, Balance, Taste, Smell, Voice, Speech, and Language Disorders.