Actively Recruiting

Age: 18Years +
All Genders
ID07424391

Impact of a Digital Training Program (Colo-ID) on Optical Histologic Prediction and Management of Colorectal Polyps: A Prospective Study

Led by Clinique Paris-Bercy · Updated on 2026-02-23

1500

Participants Needed

1

Research Sites

13 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the impact of a structured digital training program called Colo-ID on the accuracy of optical histology prediction for colorectal polyps detected during colonoscopy. The study focuses on improving the identification of polyp types using enhanced imaging, which may help optimize management strategies such as resect-and-discard for small polyps. This prospective, single-center observational study aims to assess how this training affects optical diagnosis performance in real-life clinical practice. Adults undergoing colonoscopy with at least one detected colorectal polyp will be included. During each procedure, endoscopists will record their optical prediction of the polyp's histology. All polyps will be removed and sent for standard histopathological analysis. The digital training program involves a structured educational intervention to improve endoscopists' skills in polyp characterization through image-based training and performance assessment. No patient management changes will occur due to the study. Participants will undergo routine colonoscopy with additional recording of optical diagnosis data before and after the training program. Researchers will compare optical prediction accuracy with histopathology results to measure concordance. Secondary assessments include diagnostic performance based on polyp size and location, inter-operator variability, and potential cost and environmental benefits. The study runs from February to June 2026 and maintains current patient care throughout.

CONDITIONS

Brief Title

COLO-PREDICT: Digital Training and Optical Diagnosis of Colorectal Polyps

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 6518 years
  • Patients undergoing colonoscopy in routine clinical practice at the participating center
  • At least one colorectal polyp detected during colonoscopy
  • Optical histology prediction recorded during the procedure
  • Histopathological analysis available for resected polyps (reference standard)
Not Eligible

You will not qualify if you...

  • Patients aged <18 years
  • Refusal or opposition to use of data as applicable under local regulations
  • Missing key study data such as no recorded optical prediction or no histopathology result

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - February 2026 to June 2026

Participants undergo colonoscopy during which colorectal polyps are detected and optical histology predictions are recorded as part of routine clinical practice.

1 visit (in-person) per colonoscopy procedure

Long-term Monitoring

Duration - February 2026 to June 2026

Participants are observed with data collected on polyp histopathology and optical prediction performance before and after the digital training program for endoscopists.

No additional visits beyond routine care

Trial Site Locations

Total: 1 location

1

Clinique Paris-Bercy

Charenton-le-Pont, Val de Marne, France, 94220

Actively Recruiting

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Research Team

D

David Karsenti, MD

C

Coralie Declerck, Ms.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Published Research Related To This Trial

The American Society for Gastrointestinal Endoscopy PIVI (Preservation and Incorporation of Valuable Endoscopic Innovations) on real-time endoscopic assessment of the histology of diminutive colorectal polyps.

Douglas K Rex, Charles Kahi, Michael O'Brien...

https://pubmed.ncbi.nlm.nih.gov/21353837

Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2020.

Cesare Hassan, Giulio Antonelli, Jean-Marc Dumonceau...

https://pubmed.ncbi.nlm.nih.gov/32572858

Definition of competence standards for optical diagnosis of diminutive colorectal polyps: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement.

Britt B S L Houwen, Cesare Hassan, Veerle M H Coupé...

https://pubmed.ncbi.nlm.nih.gov/34872120