Clinical effectiveness of posaconazole prophylaxis in patients with acute myelogenous leukaemia (AML): a 6 year experience of the Cologne AML cohort.
J J Vehreschild, M J G T Rüping, H Wisplinghoff...
https://pubmed.ncbi.nlm.nih.gov/20410061Actively Recruiting
Led by University Hospital of Cologne · Updated on 2013-04-01
100000
Participants Needed
1
Research Sites
N/A
Total Duration
The Cologne Cohort of Neutropenic Patients (CoCoNut) is a non-interventional observational study focused on examining risk factors, treatments, and outcomes in patients who have weakened immune systems due to neutropenia after chemotherapy for various cancers. The study collects detailed data to better understand these patients' health and infection risks. Participants in this study include immunosuppressed patients who have developed neutropenia following chemotherapy. The study observes the use and effectiveness of antiinfective drug therapies among these high-risk patients, aiming to analyze how these treatments work in real-world settings without altering their usual medical care. During the study, researchers collect comprehensive patient data over time to evaluate long-term survival outcomes, particularly looking at hematology and oncology patients two years after their last follow-up. The study involves ongoing monitoring of patient health, interventions, and any opportunistic infections, with participation lasting as long as patients continue to be followed in the cohort.
CONDITIONS
Cologne Cohort of Neutropenic Patients (CoCoNut)
You may qualify if you...
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 2 years following last follow-up
Participants who undergo routine care for neutropenia after chemotherapy are observed to collect data on risk factors, interventions, and outcomes.
Periodic visits as per routine clinical care
Total: 1 location
1
University Hospital of Cologne
Cologne, North Rhine-Westphalia, Germany, 50924
Actively Recruiting
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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https://pubmed.ncbi.nlm.nih.gov/24607558