Actively Recruiting

Age: 45Years - 75Years
All Genders
Healthy Volunteers
NCT07168876

Colon Cancer Liquid Biopsy Investigation of Methylation-based Biomarkers Evaluation Using Delta-HLD (CLIMBED)

Led by Epiliquid Holding, Inc · Updated on 2025-09-11

3200

Participants Needed

1

Research Sites

243 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

CLIMBED (Colon cancer Liquid biopsy Investigation of Methylation-based Biomarkers Evaluation using Delta-HLD) is a non-randomized, observational, cross-sectional clinical validation study designed to assess the performance of Delta-HLD, Epiliquid's proprietary liquid biopsy technology, for colorectal cancer (CRC) detection. The study will evaluate the test performance in an average-risk population for CRC undergoing screening colonoscopy, which will serve as the gold standard reference.

CONDITIONS

Official Title

Colon Cancer Liquid Biopsy Investigation of Methylation-based Biomarkers Evaluation Using Delta-HLD (CLIMBED)

Who Can Participate

Age: 45Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and women aged 45-75 years
  • Scheduled for colorectal cancer screening colonoscopy by treating physician
Not Eligible

You will not qualify if you...

  • First-degree family history of colorectal cancer
  • Inflammatory bowel disease (ulcerative colitis, Crohn's disease)
  • Other malignancies within 5 years
  • Known hereditary colorectal cancer syndromes (Lynch syndrome, familial adenomatous polyposis)
  • Major trauma, surgery, or transfusion in past 30 days
  • Current participation in an interventional clinical trial

AI-Screening

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Trial Site Locations

Total: 1 location

1

Epiliquid

Mendoza, Mendoza Province, Argentina, 5500

Actively Recruiting

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Research Team

D

Dr. Victoria Bocanegra, MD, PhD.

CONTACT

D

Dr. Emanuel Campoy, PhD.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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