Actively Recruiting
Colonoscopy Bowel Prep Comparison Among Diabetic Patients
Led by Eisenhower Army Medical Center · Updated on 2026-01-20
80
Participants Needed
1
Research Sites
27 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if the Golytely or SUPREP bowel preparation works more effectively in bowel cleansing for colorectal cancer screening with colonoscopy in patients with diabetes. The main questions this study aims to answer are: 1. Is there a significant difference in bowel prep cleanse between Golytely and SUPREP in patients with diabetes based on the Boston Bowel Prep Score (BBPS) as assessed by blinded, skilled endoscopists? 2. Is there a significant difference in patients' tolerance between the bowel preparations as assessed by the validated Mayo Bowel Prep Tolerability Form (MBPTF)? Participants will: * Be randomized to take either Golytely or SUPREP bowel preparation prior to their colonoscopy * Complete the MBPTF on the procedure date prior to the scheduled colonoscopy * Undergo a standardized screening colonoscopy during which time a blinded endoscopist will document the participant's BBPS The research team hypothesizes that SUPREP will have a significant difference in tolerability (based on MBPTF), while exhibiting no difference in bowel cleanse (based on BBPS) in the diabetic patient population.
CONDITIONS
Official Title
Colonoscopy Bowel Prep Comparison Among Diabetic Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Provided informed consent with full understanding of study requirements and risks
- Diagnosed with any type of diabetes mellitus as per current ACP guidelines
- Aged 18 years or older
- Undergoing average risk colorectal cancer screening, polyp surveillance, or have family history of cancer
You will not qualify if you...
- Unable to provide informed consent due to mental condition
- Have major systemic diseases (cardiovascular, hepatic, neurological, endocrine) that affect study participation or results
- Have persistent significant or severe infection
- Used any investigational drug in the last 6 months
- Have liver function impairment with ALT, AST, or direct bilirubin levels over twice the normal limit
- Are pregnant, breastfeeding, or plan to become pregnant during the study
- Have significantly impaired bone marrow function or blood disorders such as anemia, leukopenia, or thrombocytopenia
- History of colorectal cancer
- Diagnosed with inflammatory bowel disease
- Previous colon resection surgery
- Prior colorectal surgery
- Family history of hereditary polyposis or cancer syndromes including FAP, Gardner Syndrome, Turcot Syndrome, Lynch Syndrome, Cowden Syndrome, or Peutz-Jeghers Syndrome
- Currently have symptoms like bleeding, diarrhea, constipation, or abdominal pain
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Trial Site Locations
Total: 1 location
1
Dwight D. Eisenhower Army Medical Center
Fort Gordon, Georgia, United States, 30905
Actively Recruiting
Research Team
D
Darrell F Barker MD, FACG, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SCREENING
Number of Arms
2
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