Actively Recruiting
Colonoscopy Bowel Prep Comparison Among Diabetic Patients: Golytely vs. SUPREP
Led by Eisenhower Army Medical Center · Updated on 2026-01-20
80
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effectiveness and patient tolerance of two bowel preparation medications, Golytely and SUPREP, for colon cleansing in diabetic patients undergoing colorectal cancer screening with colonoscopy. The study aims to determine if there is a meaningful difference in bowel cleanliness using the Boston Bowel Prep Score (BBPS) and in patient tolerance assessed by the Mayo Bowel Prep Tolerability Form (MBPTF). Participants will be randomly assigned to take either Golytely or SUPREP before their scheduled colonoscopy. On the day of the procedure, they will complete a questionnaire measuring their experience with the bowel preparation. During the colonoscopy, a blinded, skilled endoscopist will assess bowel cleanliness using the BBPS. Throughout the trial, participants will undergo a standardized colonoscopy procedure with evaluations of bowel cleanliness and tolerability. The main outcomes measured are the quality of bowel cleansing during the colonoscopy and the participant’s tolerability score before the procedure. This study is sponsored by Eisenhower Army Medical Center and is planned to run until July 2026.
CONDITIONS
Brief Title
Colonoscopy Bowel Prep Comparison Among Diabetic Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants who have signed informed consent after understanding the study risks and requirements
- Diagnosed with diabetes according to current guidelines (any type)
- Aged 18 years or older
- At average risk for colorectal cancer, including those with polyp surveillance or family history of cancer
You will not qualify if you...
- Unable to provide informed consent due to mental condition
- Having serious cardiovascular, liver, neurological, endocrine, or other major systemic diseases that could cause risk or interfere with the study
- Persistent significant or severe infections
- Use of any investigational drug in the past 6 months
- Liver function impairment with certain elevated liver enzymes beyond twice the normal limit
- Pregnant, breastfeeding, or planning pregnancy during the study
- Significantly impaired bone marrow function or blood disorders confirmed by lab tests
- History of colorectal cancer
- Inflammatory bowel disease
- Past colorectal surgery
- Family history of hereditary polyposis or cancer syndromes such as FAP, Gardner Syndrome, Turcot Syndrome, Lynch Syndrome, Cowden Syndrome, or Peutz-Jeghers Syndrome
- Current symptoms like bleeding, diarrhea, constipation, or abdominal pain indicating active issues related to colon health
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit
Duration - Short duration prior to colonoscopy
Participants receive bowel preparation using either Golytely or SUPREP before their screening colonoscopy to assess bowel cleanliness and tolerability.
1 visit (in-person) on the day of the colonoscopy
Trial Site Locations
Total: 1 location
1
Dwight D. Eisenhower Army Medical Center
Fort Gordon, Georgia, United States, 30905
Actively Recruiting
Research Team
D
Darrell F Barker MD, FACG, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SCREENING
Number of Arms
2
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