Actively Recruiting

Age: 45Years - 75Years
All Genders
NCT07148297

Colorectal Analysis for Signature Cancer Assessment Using Delta-HLD

Led by Epiliquid Holding, Inc · Updated on 2025-08-29

600

Participants Needed

1

Research Sites

282 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

CASCADE (Colorectal Analysis for Signature Cancer Assessment Using delta-HLD Technology) is a proof-of-concept case-control study designed to evaluate the performance of delta-HLD, Epiliquid's proprietary liquid biopsy technology, for the detection of colorectal cancer. Epiliquid also integrates a proprietary bioinformatic system capable of identifying, ranking, and selecting tumor-specific methylation biomarkers for different cancer types. In this study, colorectal cancer-specific biomarkers will be evaluated in blood and tissue samples using delta-HLD technology, which enables sensitive and multiplexed detection through PCR. Study results will support the validation of Epiliquid's integrated platform as a minimally invasive and accessible diagnostic solution for colorectal cancer.

CONDITIONS

Official Title

Colorectal Analysis for Signature Cancer Assessment Using Delta-HLD

Who Can Participate

Age: 45Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Candidate for colonoscopy or colorectal surgery
  • Willing and able to provide informed consent
  • Able to provide blood and/or tissue sample before treatment or resection
Not Eligible

You will not qualify if you...

  • Prior history of colorectal cancer
  • Inflammatory bowel disease
  • Known hereditary cancer syndromes (e.g., Lynch, FAP)
  • Other active malignancies
  • Recent chemotherapy or immunosuppressive treatment

AI-Screening

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Trial Site Locations

Total: 1 location

1

Epiliquid

Mendoza, Argentina, 5500

Actively Recruiting

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Research Team

D

Dr. Victoria Bocanegra, MD, PhD.

CONTACT

D

Dr. Emanuel Campoy, PhD.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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