Actively Recruiting

Phase Not Applicable
Age: 50Years - 75Years
All Genders
NCT07274735

Combined Effects of INF and OEP in Patients With Diabetic Peripheral Neuropathy

Led by Riphah International University · Updated on 2025-12-10

65

Participants Needed

1

Research Sites

65 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

DPN often leads to balance issues, sensory deficits, and chronic pain, which can severely impact daily functioning and independence. INF therapy aims to improve nerve blood flow and alleviate neuropathic symptoms through manual techniques, while the Otago Exercise Program focuses on enhancing strength and balance to reduce fall risk. By comparing these two interventions, this study seeks to identify effective strategies that can improve balance, reduce pain, and enhance the quality of life for individuals suffering from DPN

CONDITIONS

Official Title

Combined Effects of INF and OEP in Patients With Diabetic Peripheral Neuropathy

Who Can Participate

Age: 50Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 50 to 75 years
  • Male and female patients
  • Diagnosed with type 2 diabetes mellitus
  • DN4 neuropathic pain score of 4 or higher
  • Timed Up-and-Go (TUG) test score less than 15 seconds
  • Able to walk at least 10 meters
Not Eligible

You will not qualify if you...

  • Presence of systemic diseases other than diabetes (e.g., end-stage renal failure, uncontrolled hypertension, severe dyslipidemia, chronic liver disease, autoimmune disease, advanced COPD)
  • Documented active alcohol or drug misuse
  • Total or partial lower extremity amputation
  • Morbid obesity or pregnancy (self-reported)
  • Active inflammation or inflammatory neuropathies including chronic inflammatory demyelinating polyneuropathy, proximal diabetic neuropathy, chemotherapy-induced peripheral neuropathy, autonomic neuropathies, or neuropathies not related to diabetes such as B12 deficiency

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Rasheed Hospital

Lahore, Punjab Province, Pakistan, 54800

Actively Recruiting

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Research Team

I

Imran Amjad, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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Combined Effects of INF and OEP in Patients With Diabetic Peripheral Neuropathy | DecenTrialz