Combined Effect of Intraneural Facilitation Therapy and Otago Exercise on Pain, Balance, and Quality of Life in Patients with Diabetic Peripheral Neuropathy

What this Trial Is About

Researchers are studying diabetic peripheral neuropathy (DPN), a condition that often causes balance problems, sensory loss, and chronic pain, affecting daily life and independence. The trial compares intraneural facilitation (INF) therapy and the Otago Exercise Program (OEP) to identify which approach better improves balance, reduces pain, and enhances quality of life for people with DPN. This study aims to fill a knowledge gap by directly comparing these two therapies in DPN patients. The trial involves three groups receiving different interventions over eight weeks. One group receives intraneural facilitation therapy with 24 sessions, three times weekly, each lasting 50-60 minutes. Another group participates in Otago exercise training three times a week for 50 minutes per session, including warm-up, cool-down, strengthening, and balance exercises. The third group combines both therapies with sessions three times a week, mixing 20-30 minutes of OEP and 20-30 minutes of INF therapy per session. Effects are measured at the start, after four weeks, and after eight weeks. Participants will be assessed using various tests such as the DN4 pain scale, Mini BESTest for balance, and quality of life questionnaires specific to diabetic neuropathy at the 8-week point. Additional measures include pain rating scales, Timed Up-and-Go test, and ankle brachial index. The study includes monitoring of balance, pain, and quality of life improvements. Total participation lasts eight weeks with evaluations at baseline, mid, and end points to track progress and effects of the therapies.

Combined Effects of INF and OEP in Patients With Diabetic Peripheral Neuropathy