Effect of Combined Intrathecal Dexmedetomidine and Adductor Canal Block on Pain Relief After Knee Replacement Surgery

What this Trial Is About

Researchers are evaluating the effect of combining intrathecal dexmedetomidine with an adductor canal block to manage pain after total knee arthroplasty TKA. This study aims to improve postoperative pain control, helping patients recover faster and reduce complications. The study focuses on analgesia after knee surgery, involving adults aged 18 to 75 years with specific health criteria. Participants are randomly assigned to one of three groups one receiving intrathecal dexmedetomidine with bupivacaine and a saline adductor canal block, another receiving bupivacaine intrathecally with an active bupivacaine adductor canal block, and a third group receiving both intrathecal dexmedetomidine and an active bupivacaine adductor canal block. All treatments are given at the end of surgery under spinal anesthesia. During the study, researchers will monitor total morphine use and pain levels for 48 hours after surgery, as well as heart rate and blood pressure in the first hour after anesthesia. Patient satisfaction and any side effects will also be assessed. The study uses a double-blind design and measures outcomes to better understand pain relief methods after knee replacement surgery.

Combined Intrathecal Dexmedetomidine and Adductor Canal Block for Analgesia After Total Knee Arthroplasty