Actively Recruiting
Testing Combined Neurofeedback and TMS Treatments for Alcohol Use Disorder in Adults Aged 19 to 65
Led by Auburn University · Updated on 2025-10-07
90
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating the effectiveness of a combined neurofeedback and transcranial magnetic stimulation TMS intervention for individuals receiving treatment for Alcohol Use Disorder. This study aims to assess how these techniques may influence alcohol use, craving, community functioning, employment status, aggression, antisocial behavior, and brain activity over time. Participants will be randomly assigned to one of several groups receiving four weekly sessions of different combinations of active or sham TMS and neurofeedback using fMRI. The TMS involves 10 Hz pulses delivered to the right dorsolateral prefrontal cortex. Neurofeedback sessions provide real-time brain activity information either from the participant or others. A control group will receive typical treatment without TMS or neurofeedback. Participants will attend an initial visit followed by weekly intervention sessions for four weeks. Monthly remote follow-ups will occur for up to 12 months, with MRI follow-ups at 6 and 12 months. Researchers will measure changes in alcohol use, craving, social and employment outcomes, behavior, and brain structure and function throughout the study period. Safety and adherence will be monitored continuously.
CONDITIONS
Brief Title
A Combined Neurofeedback-TMS Intervention for Alcohol Use Disorder
Research Team
S
SCAMPI Lab
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