Actively Recruiting
A Combined Treatment of Manual Therapy and Nervous Vagus Stimulation in Patients With Myogenic Temporomandibular Disorders
Led by University of Alcala · Updated on 2026-05-01
60
Participants Needed
3
Research Sites
267 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Temporomandibular disorders (TMD) are one of the most important Public Health issues in the world and its incidence has increased over the years. The Physiotherapy and manual therapy techniques has shown its efficacy to reduce pain and to improve jaw functionality in patients with TMD. Until now, treatment targets has been the muscle and joint, but clinicians has not taken into account the innervation and how the nerve can have an influence in pain or jaw functionality. In this sense, it is known that there is a relationship between jaw innervation and vagus nerve, a parasympathetic nerve which is easily stimulable, due to its connection with the respiratory system, taking deep breaths using the diaphragm. Therefore, our hypothesis is that a treatment in which clinicians combine manual therapy and nerve vagus stimulation could have better effects (reducing pain, increasing range of motion in temporomandibular joints and improving quality of life in patients with TMD) than a isolated manual therapy treatment. With this purpose will be selected 20 subjects to participate in our study divided in two groups. Both groups will received 4 sessions of physiotherapy (one each 7 days during one month) and also will be thought to do own treatment those days the subjects does not come to the clinic until the study will have finished (the interventional period last two months). Both groups will received the same manual therapy techniques but only the experimental group will be treated with nerve vagus stimulation technique. One member of the group who will not participated in the interventions will be in charge of do evaluations (1 each month/ a total of 3 evaluations) following different questionaries to assess the primary variables of the study: chronic pain level, jaw functionality, physical symptoms level, range of motion and distress level.
CONDITIONS
Official Title
A Combined Treatment of Manual Therapy and Nervous Vagus Stimulation in Patients With Myogenic Temporomandibular Disorders
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of myogenic pain according to the CD / TTM diagnostic criteria
- Presence of pain during the last 30 days
- Patients with decreased jaw function and mobility due to pain
- Patients who have not received physiotherapy treatment in the last 3 weeks
- Patients of legal age
You will not qualify if you...
- Patients with drug treatment: sedatives, anti-inflammatories, antidepressants, anxiolytics or muscle relaxants
- Patients with cardiac pacemakers and implanted defibrillators
- Patients diagnosed with severe cardiorespiratory and/or respiratory diseases, cancer, infections, or systemic pathologies
- Clinical diagnosis of temporomandibular disorder of joint or mixed origin
- Patients with psychiatric or psychological disorders, intellectual or motor deficiencies preventing correct exercise, following instructions, or understanding questionnaires
- Patients with dental procedures scheduled during the study or surgery in the last 3 months
- Patients whose pain is due to local or general trauma
- Patients diagnosed with fibromyalgia, neuropathic pain, or degenerative diseases
AI-Screening
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Trial Site Locations
Total: 3 locations
1
Clinical University Physiotherapy and pain
Alcalá de Henares, Madrid, Spain, 2805
Actively Recruiting
2
Martinez-Merinero, Patricia
Alcalá de Henares, Madrid, Spain, 28805
Actively Recruiting
3
Physioterapy and Pain center research
Alcalá de Henares, Madrid, Spain, 28805
Actively Recruiting
Research Team
P
Patricia Martinez-Merinero, PhD
CONTACT
D
Daniel Pecos-Martin, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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