Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
FEMALE
NCT07070791

Combined Upper Extremity Resistance and Aerobic Exercise Training in Patients With Breast Cancer

Led by Hacettepe University · Updated on 2025-12-29

40

Participants Needed

1

Research Sites

51 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

According to updated data from the International Agency for Research on Cancer (IARC) for 2022, breast cancer in women is responsible for one in four cancer cases and one in six cancer deaths worldwide and is the second leading cause of global cancer incidence, accounting for 11.6% of all cancer cases, and the fourth leading cause of cancer deaths worldwide, accounting for 6.9% of all cancer deaths. During or after breast cancer treatments, there is exposure to a variety of direct (local/regional treatment, systemic treatment and supportive care) and indirect factors (modifiable and non-modifiable risk factors) that may have adverse effects on treatment-related haematological, cardiovascular, pulmonary and musculoskeletal components. Upper limb dysfunction and lymphoedema have been reported to be two of the most common side effects affecting the quality of life of breast cancer patients after breast cancer treatments. The elastic resistance band, which is widely used in strength training, has the advantage of being applied to various classes because it provides resistance angles in various postures and has a low risk of injury. However, few studies have been conducted on elastic resistance band application in patients with breast cancer. At the same time, evidence on the effectiveness of upper extremity aerobic exercise training in patients with breast cancer is limited. Therefore, this study aimed to investigate the effects of upper extremity aerobic exercise training combined with progressive resistance training and upper extremity aerobic exercise training alone on upper extremity exercise capacity, upper extremity functionality, sarcopenia, frailty, quality of life and lymphedema in patients with breast cancer.

CONDITIONS

Official Title

Combined Upper Extremity Resistance and Aerobic Exercise Training in Patients With Breast Cancer

Who Can Participate

Age: 18Years - 80Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Be between 18 and 80 years old
  • Volunteer to participate in the research
  • At least 15 months have passed since breast cancer surgery
  • Able to read and understand the scales and cooperate with tests
  • Physically inactive, doing less than 60 minutes of structured exercise per week
Not Eligible

You will not qualify if you...

  • Have an active infection
  • Have bilateral breast cancer
  • Have surgical, neurological, or orthopedic problems affecting upper limb function besides breast cancer surgery
  • Have a neurological disease or clinical condition affecting cognitive status
  • Have musculoskeletal or neurological diseases that affect exercise performance
  • Have symptomatic heart disease, previous lung surgery, or other malignant diseases
  • Have unstable hypertension or diabetes mellitus

AI-Screening

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Trial Site Locations

Total: 1 location

1

Hcettepe University

Ankara, State, Turkey (Türkiye), 06100

Actively Recruiting

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Research Team

E

Ebru Calik Kutukcu, PhD

CONTACT

N

Naciye Vardar-Yagli, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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