Actively Recruiting
The Combined Use of PRP with Lipoaspirate And/or Bone Marrow Aspirate in Osteoarthritis
Led by Dr. Grant M. Pagdin · Updated on 2024-11-15
240
Participants Needed
1
Research Sites
378 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To demonstrate the efficacy of the combined use of platelet-rich plasma (PRP) with lipoaspirate and/or bone marrow aspirate in osteoarthritis of major joints, and to compare the outcomes achieved using three combinations: PRP plus lipoaspirate, PRP plus bone marrow aspirate, and PRP plus both lipoaspirate and bone marrow aspirate.
CONDITIONS
Official Title
The Combined Use of PRP with Lipoaspirate And/or Bone Marrow Aspirate in Osteoarthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Capable of providing written informed consent and willing and able to follow the study requirements
- Male or female aged 19 years or older at consent
- Osteoarthritis in a major joint confirmed by imaging (x-ray or MRI) within the last year
- Kellgren & Lawrence Grades 1 to 3 osteoarthritis
You will not qualify if you...
- Body mass index (BMI) greater than 35
- Arthroscopic surgery to the treatment joint within the past 12 months
- Cortisone or hyaluronic acid injection in the treatment joint within 3 months prior to stem cell injection
- Unable to hold antiplatelet therapy as directed before the procedure
- Kellgren & Lawrence Grade 4 osteoarthritis
- Platelet count less than 100 x 10^9
- Hemoglobin less than 100 g/L
- Active infection with fever or elevated white blood cell count
- Active cancer diagnosis
- Autoimmune disorders such as rheumatoid arthritis or lupus
- Pregnant women (due to potential fetal harm from x-rays); women who become pregnant during the study will stop treatment and imaging but may continue symptom follow-up
- Allergies to lidocaine, heparin, or epinephrine
AI-Screening
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Trial Site Locations
Total: 1 location
1
Pagdin Health
Kelowna, British Columbia, Canada, V1Y 6T8
Actively Recruiting
Research Team
G
Grant Pagdin, MD
CONTACT
M
Michelle Murtha, MScN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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