Evaluating Combined Angio-CT and MRI Guidance for Transarterial Microembolization in Chronic Shoulder and Knee Pain Management

What this Trial Is About

Researchers are evaluating a new minimally invasive treatment called Transarterial Microembolization TAME for people with chronic musculoskeletal pain, especially in the shoulder or knee joints. This treatment focuses on blocking abnormal new blood vessel growth that may contribute to pain. The study aims to improve treatment planning and guidance by combining information from magnetic resonance imaging MRI and fused computed tomography CT with angiography to better target the painful areas and assess treatment outcomes. All participants will receive the TAME procedure targeting abnormal blood vessels in their affected shoulder or knee. Patients are categorized as responders if their pain decreases by two points or more on the Visual Analogue Scale VAS one month after treatment. Those with less than two points reduction or increased pain are considered non-responders. The study uses advanced imaging techniques to guide the procedure and monitor treatment effectiveness. Participants will be monitored for pain relief on day 0, day 1, week 1, and at 1, 3, and 6 months after treatment. Functional improvements in shoulder or knee joints will also be assessed at these time points. Researchers will collect imaging data and clinical evaluations to measure pain and joint function over time. The total participation duration extends to at least six months to evaluate both short- and longer-term treatment effects.

The Combined Utility of Angio-CT and MRI in Managing Chronic Musculoskeletal Pain: a Prospective Study to Evaluate the Efficacy of Transarterial Microembolization