Actively Recruiting
Combining Aspirin With Cilostazol or Clopidogrel in Minor Stroke or TIA
Led by Kafrelsheikh University · Updated on 2024-09-19
870
Participants Needed
1
Research Sites
128 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Along with the current clinical trial, the efficacy and safety of a 300 mg loading dose of clopidogrel administered within 24 hours of the first-ever minor stroke or TIA compared to 200 mg cilostazol were assessed through NIHSS, mRS, and possible adverse effects
CONDITIONS
Official Title
Combining Aspirin With Cilostazol or Clopidogrel in Minor Stroke or TIA
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 75 years
- First-ever presentation with minor ischemic stroke or transient ischemic attack (TIA)
- Received antiplatelet treatment within 24 hours of ischemic stroke onset
- Not eligible for rt-PA treatment
- Both genders included
You will not qualify if you...
- Lack of follow-up for 90 days after enrollment
- NIHSS score less than 5 or rapidly resolving symptoms before imaging
- History of persistent or recurrent central nervous system diseases (e.g., epilepsy, meningioma, multiple sclerosis, head trauma with residual deficits)
- Clinical seizures at stroke onset
- Symptoms of major organ failure or active malignancies
- Acute myocardial infarction within previous six weeks
- Use of warfarin, regular ticagrelor in the week before admission, or chemotherapy within the past year
- Active peptic ulcers, gastrointestinal surgery, or bleeding history within the last year
- Major surgery within the last three months
- Known allergy to study drugs
- INR greater than 1.4 or PT greater than 18
- Blood glucose less than 50 or greater than 400 mg/dL
- Blood pressure less than 90/60 or greater than 185/110 mmHg on admission
- Platelet count less than 100,000
- Pregnancy or lactation
- Stroke due to venous thrombosis or stroke following cardiac arrest or severe low blood pressure
- Contraindications to study drugs
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Kafr Elsheikh University Hospital
Kafr ash Shaykh, Egypt, 33511
Actively Recruiting
Research Team
M
mohamed G. Zeinhom, MD
CONTACT
S
sherihan R. ahmed, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here