Actively Recruiting
Combining Aspirin With Ticagrelor or Cilostazol in Minor Stroke or TIA
Led by Kafrelsheikh University · Updated on 2024-09-19
900
Participants Needed
1
Research Sites
137 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Along with the current clinical trial, the efficacy and safety of a 180 mg loading dose of ticagrelor administered within 24 hours of the first-ever minor stroke or TIA compared to 200mg cilostazol were assessed through NIHSS, mRS, and possible adverse effects.
CONDITIONS
Official Title
Combining Aspirin With Ticagrelor or Cilostazol in Minor Stroke or TIA
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 75 years
- Both genders
- First-ever minor ischemic stroke or transient ischemic attack
- Received antiplatelet treatment within 24 hours of stroke onset
- Not eligible for rt-PA treatment
You will not qualify if you...
- Not followed up for 90 days after enrollment
- NIHSS less than 5 or rapidly resolving symptoms before imaging
- Known persistent or recurrent central nervous system disorders (e.g., epilepsy, meningioma, multiple sclerosis, head trauma with neurological deficit)
- Clinical seizures at stroke onset
- Major organ failure symptoms
- Active cancer or acute myocardial infarction within past 6 weeks
- Use of warfarin, regular ticagrelor in the week before admission, or chemotherapy in the past year
- Active peptic ulcer, gastrointestinal surgery, or bleeding history within last year
- Major surgery within past 3 months
- Allergy to study drugs
- INR greater than 1.4 or PT greater than 18
- Blood glucose less than 50 or greater than 400 mg/dL
- Blood pressure less than 90/60 or greater than 185/110 mmHg on admission
- Platelet count less than 100,000
- Pregnant or lactating patients
- Stroke due to venous thrombosis or following cardiac arrest or profuse hypotension
- Contraindications to study drugs
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Kafr Elsheikh University Hospital
Kafr ash Shaykh, Egypt, 33511
Actively Recruiting
Research Team
M
mohamed G. Zeinhom, MD
CONTACT
S
sherihan R. ahmed, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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