Actively Recruiting

Phase 1
Phase 2
Age: 18Years - 60Years
All Genders
NCT06970678

Combining Dexmedetomidine Infusion and Paragastric Autonomic Neural Block to Enhance Postoperative Recovery in Patients Undergoing Laparoscopic Sleeve Gastrectomy

Led by Alexandria University · Updated on 2025-05-14

46

Participants Needed

1

Research Sites

10 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if combining Dexmedetomidine infusion and paragastric autonomic neural block will enhance the postoperative recovery of patients undergoing laparoscopic sleeve gastrectomy. The main questions it aims to answer are: Will combining the two techniques (Dexmedetomidine infusion and paragastric autonomic neural block) improve the quality of recovery? Will opioid consumption postoperatively decrease after combining those two techniques? Will the patients be able to start mobilizing sooner after surgery? Will the patient encounter less incidence of nausea and vomiting? Researchers will asses the quality of the patients' recovery by reviewing the Quality of recovery 40 (QoR 40) questionnaire filled by the patients, assessing hemodynamic parameters intra- and postoperatively, recording the opioids consumed by the patients in the postoperative period, recording the time to first mobilization of the patient, and recording the incidence of nausea and vomiting.

CONDITIONS

Official Title

Combining Dexmedetomidine Infusion and Paragastric Autonomic Neural Block to Enhance Postoperative Recovery in Patients Undergoing Laparoscopic Sleeve Gastrectomy

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • ASA physical status II or III
  • Age between 18 and 60 years
  • Body mass index (BMI) between 35 and 50 kg/m²
Not Eligible

You will not qualify if you...

  • Chronic pain disorders
  • Use of gabapentin or chronic opioid use
  • Anticoagulant therapy
  • History of upper gastrointestinal system surgery
  • Liver, kidney, or cardiovascular diseases
  • Allergy to dexmedetomidine or bupivacaine

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Alexandria Main University Hospital

Alexandria, Egypt

Actively Recruiting

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Research Team

M

Mai A El-Sayed, Lecturer of Anesthesia

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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