Actively Recruiting
Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke
Led by Northwestern University · Updated on 2025-08-22
70
Participants Needed
1
Research Sites
309 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will examine the combination of myoelectric computer interface (MyoCI) training with targeted memory reactivation (TMR) in chronic stroke survivors. The study aims to determine whether this training-plus-sleep combination will generalize to improve arm motor function over an extended training protocol in stroke survivors.
CONDITIONS
Official Title
Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age at enrollment is 21 or older
- Hemiparesis from first ever stroke affecting arm movement at least 6 months prior to screening
- Severe to moderate motor impairment (FMA-UE of 7-40)
- At least some voluntary shoulder and elbow muscle activation
You will not qualify if you...
- Inability to follow instructions of the MyoCI task
- Visual impairment such as hemianopia preventing full view of screen
- Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on NIH Stroke Scale Extinction and Inattention subtest)
- Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study
- Inability to understand or follow commands in English due to aphasia or other reason
- Diffuse or multifocal infarcts in both hemispheres
- Substantial arm pain preventing participation for 90 minutes a day
- Spasticity treatment (pharmacological or Botox) within last 3 months
- Ferromagnetic implants that are MRI incompatible
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Northwestern University
Chicago, Illinois, United States, 60611
Actively Recruiting
Research Team
M
Marc W Slutzky, MD/PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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