Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06429956

Combining Treatment Components in Transdiagnostic Therapy for Anxiety and Depression

Led by University of Aarhus · Updated on 2025-11-28

93

Participants Needed

1

Research Sites

100 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The present study is a randomized controlled trial that will evaluate the effect of combining two treatment components (i.e., cognitive restructuring and detached mindfulness) drawn from cognitive behavioral therapies (CBTs) that are often combined in clinical practice. However, knowledge about the effect of combining these treatment components is lacking. Therefore, this study aims to explore single, combined, and sequencing effects of these two treatment components in patients with depression and/or anxiety disorders. Furthermore, the study aims to explore possible demographic and clinical moderators of the effects to address the question of what works for whom.

CONDITIONS

Official Title

Combining Treatment Components in Transdiagnostic Therapy for Anxiety and Depression

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Diagnosis of anxiety disorder (generalized anxiety disorder, social anxiety disorder, or panic disorder with or without agoraphobia) and/or mild to moderate major depressive disorder according to DSM-5
  • Proficient in Danish language
  • Able and willing to give informed consent
  • No medication or stable antidepressant/antianxiety medication with same dosage for 8 weeks or more
  • Access to a smartphone, tablet, or computer with a video camera
Not Eligible

You will not qualify if you...

  • Severe depression requiring more intense psychotherapy or medication
  • Persistent depressive disorder with symptoms lasting 2 years or more
  • Unstable medication dosage
  • Currently receiving other psychotherapy or counseling
  • Unable to participate online
  • Not proficient in Danish language
  • History of bipolar disorder
  • Current or past psychosis
  • Substance abuse or dependence requiring treatment
  • Suicide risk requiring immediate hospitalization

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Psychology and Behavioral Sciences

Aarhus, Denmark, 8000

Actively Recruiting

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Research Team

C

Caroline Nørskov, MSc

CONTACT

M

Mia O'Toole, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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