Testing a New Combined Cognitive Behavioral and Physical Activity Program to Reduce Fatigue in Adults with Inflammatory Arthritis in Denmark and Sweden

What this Trial Is About

Researchers are evaluating a new combined fatigue intervention COMFI for people with inflammatory arthritis IA, including rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis. Fatigue is a common and severe problem in IA patients, affecting their quality of life and ability to work. This study aims to test if combining a cognitive behavioral approach and physical activity can reduce fatigue severity and impact in patients from Denmark and Sweden. The COMFI intervention is a 24-week outpatient program consisting of six group sessions based on cognitive behavioral approaches covering topics such as fatigue, physical activity, energy management, and peer support. A seventh booster group session is held at week 24, along with an optional individual session between weeks 6 and 9, and a support line available from weeks 13 to 23. Participants join groups of 8-10 people, with the intervention tested in four groups across two sites. Participants will complete patient-reported fatigue outcome measures at baseline, 3, 6, and 12 months, using questionnaires and databases. Physical activity and fitness will be measured at baseline and 6 months. Attendance and time use will be recorded by health professionals. The study also includes two focus group interviews for qualitative evaluation. Data confidentiality and ethical standards are maintained throughout the study, which will provide insights into the feasibility and meaningfulness of the intervention for IA patients.

COMFI - a COMbined Fatigue Intervention