Actively Recruiting

Phase Not Applicable
Age: 21Years +
All Genders
Healthy Volunteers
NCT06787937

Communicating About Nicotine Reduction in Cigarettes

Led by Georgia State University · Updated on 2025-10-29

1230

Participants Needed

2

Research Sites

176 weeks

Total Duration

On this page

Sponsors

G

Georgia State University

Lead Sponsor

E

Emory University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn how a messaging campaign about reduced nicotine cigarettes and policy, combined with the use of very low nicotine cigarettes (VLNCs), affects smoking behavior and attitudes among adult smokers. The study also aims to assess the efficacy of the messages in different populations, including smokers with past-month serious psychological distress (SPD), low socioeconomic status (SES), and those in neither category. The primary hypothesis is: exposure to messages in combination with VLNC use will lead to less cigarettes use compared to VLNCs without messages. Researchers will compare: The effects of receiving VLNCs with messages (treatment group) to receiving VLNCs without messages (control group). Participants will: Complete a baseline survey and be randomly assigned to one of two groups: treatment (VLNCs + messages) or control (VLNCs only). Attend weekly study visits for surveys, breath samples, and receive supply of VLNCs , either with or without the messaging campaign. Complete brief daily surveys through text messages.

CONDITIONS

Official Title

Communicating About Nicotine Reduction in Cigarettes

Who Can Participate

Age: 21Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 21+ years
  • Current smoker having smoked 100 cigarettes in lifetime
  • Smoking at least 27 days out of past 30 days
  • Expired breath carbon monoxide level of 6 ppm or higher to confirm regular smoking
  • Able to speak, read, and write English
  • Available for the full study period
  • Willing to try novel research cigarettes
Not Eligible

You will not qualify if you...

  • Pregnant or breastfeeding
  • Living in the same household as another study participant
  • Not willing to use research cigarettes during the trial

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Georgia State university

Atlanta, Georgia, United States, 30303

Actively Recruiting

2

Emory University

Atlanta, Georgia, United States, 30322

Actively Recruiting

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Research Team

L

Lyudmila Popova, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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