Study of Two Speech Therapy Approaches for Adults with Primary Progressive Aphasia Using Communication Bridge

What this Trial Is About

Researchers are evaluating two evidence-based speech-language therapy treatments for adults with mild to moderate Primary Progressive Aphasia PPA. The study aims to better understand how these therapies affect communication abilities in people with PPA. It uses a randomized controlled trial design and involves participants and their engaged care partners. Participants will receive a laptop with necessary applications and access to Communication Bridge, a personalized web program to practice home exercises supporting the therapy. They will attend up to 20 speech therapy sessions with a licensed speech therapist and undergo up to 10 evaluations over about 17 months. The study compares an experimental dyadic intervention involving both the person with PPA and their partner, with a control intervention focusing on the person with PPA alone using fixed speech therapy activities. During the study, participants will complete assessments of communication participation and caregiver burden at five time points up to 18 months. The study includes regular monitoring through interviews, standardized tests, and use of the web application. There are no costs to participate, and medical records will be reviewed to confirm eligibility.

Communication Bridge 3 Study