Actively Recruiting

Phase 2
Age: 18Years - 100Years
All Genders
NCT06191198

Communication Bridge 3 Study

Led by University of Chicago · Updated on 2025-05-30

200

Participants Needed

1

Research Sites

203 weeks

Total Duration

On this page

Sponsors

U

University of Chicago

Lead Sponsor

W

Western University, Canada

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study will use a randomized controlled trial design to evaluate the effect of two evidence-based treatments for adults with mild-moderate Primary Progressive Aphasia (PPA). The aim of the study is to help us better understand the effects of speech-language therapy on communication abilities in individuals with PPA.

CONDITIONS

Official Title

Communication Bridge 3 Study

Who Can Participate

Age: 18Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of Primary Progressive Aphasia confirmed by a neurologist and medical records
  • English as the primary language used in daily communication
  • Adequate hearing (with or without aids) for communication in crowded environments
  • Adequate vision (with or without aids) for reading functional materials
  • Ability to pass technology screening and use video conferencing and Communication Bridge™ web application
  • Geriatric Depression Scale score of 9 or less
  • Mild to moderate PPA confirmed by speech-language pathologist evaluation and standardized testing
  • Communication partner aged 18 or older
  • Communication partner uses English as primary language
  • Communication partner has adequate hearing for communication in crowded environments
  • Communication partner can pass technology screening and use required applications
Not Eligible

You will not qualify if you...

  • Diagnosis of dementia other than Primary Progressive Aphasia
  • Concurrent participation in an outside speech language therapy program during the study
  • Communication partners with pre-existing communication impairments such as aphasia or dementia that would affect participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Chicago - American School Building

Chicago, Illinois, United States, 60637

Actively Recruiting

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Research Team

M

Matthew Bona, MPH

CONTACT

E

Emily Cummings

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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