Actively Recruiting
Community Antibiotic Use, Susceptibility and ResisTance Among Patients With Urinary Tract Infections (CAST-UTI)
Led by St George's, University of London · Updated on 2025-06-10
3000
Participants Needed
1
Research Sites
81 weeks
Total Duration
On this page
Sponsors
S
St George's, University of London
Lead Sponsor
M
Makerere University
Collaborating Sponsor
AI-Summary
What this Trial Is About
1. General objective This pilot study aims to compare the prevalence of resistance in bacteria causing UTIs among patients seeking care outside the hospital settings (CDROs) to the WHO-GLASS data. 2. Specific objectives 2-1 Primary objectives: * Determine the resistance profiles of uropathogens and carriage strains from patients with uncomplicated UTIs attending community drug retail outlets (CDRO's) and in hospitals\*. * Compare the resistance profiles of the uropathogens from patients with uncomplicated UTIs attending CDROs and hospitals to those in the WHO-GLASS database. * Explore the patient pathway and its impact on antibiotic use among patients presenting to CDROs and hospitals with uncomplicated UTIs. * Determine the appropriateness of antimicrobial use in the treatment of uncomplicated UTIs among patients presenting to CDROs and hospitals 2-2 Secondary objectives: * Compare resistance profiles among the uropathogens from patients from two neighbourhoods in Kampala. * Examine environmental samples between the study sites to determine the presence of antibiotic residues and AMR two neighbourhoods in Kampala.
CONDITIONS
Official Title
Community Antibiotic Use, Susceptibility and ResisTance Among Patients With Urinary Tract Infections (CAST-UTI)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Must have one or more of the following clinical presentations regardless of age: acute (< 2 weeks) dysuria, increased urinary urgency and frequency, irritation, discharge, increased lower abdominal pain or discomfort, or sometimes gross haematuria
- In elderly patients with pre-existing urinary symptoms: increased acute urinary changes
You will not qualify if you...
- People without symptoms of urinary tract infection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Infectious Diseases Research Collaboration (IDRC), Uganda
Kampala, Central Region, Uganda, PO Box 7475
Actively Recruiting
Research Team
C
Catrin E Moore, DPhil, MBA, MSc, BSc, FRSB, FI
CONTACT
H
Henry Kajumbula, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here