Actively Recruiting

Phase Not Applicable
Age: 40Years - 90Years
All Genders
NCT04252950

Community-based Exercise Following Revascularization for PAD

Led by University of Minnesota · Updated on 2025-09-19

30

Participants Needed

1

Research Sites

229 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The primary goal of this clinical trial is to evaluate whether a community-based structured exercise therapy (CB-SET) intervention, which could be accessible and easily disseminated, adds benefit to peripheral artery disease (PAD) patients undergoing revascularization (REVASC) to improve their function and cardiovascular health.

CONDITIONS

Official Title

Community-based Exercise Following Revascularization for PAD

Who Can Participate

Age: 40Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients receiving revascularization for aorto-iliac and/or femoral-popliteal disease in at least one limb
  • Patients with focal and/or diffuse peripheral artery disease
  • Patients with bilateral revascularization
  • Ability to participate in an exercise program
Not Eligible

You will not qualify if you...

  • Lower limb amputations that affect treadmill walking
  • Critical limb ischemia defined by rest pain or ulcers/gangrene on lower limbs
  • Peripheral artery disease from non-atherosclerotic causes (e.g., fibromuscular dysplasia)
  • Coronary artery bypass graft or major surgery within 6 months prior to screening
  • Walking limited mainly by chronic lung disease, angina, or heart failure symptoms
  • Myocardial infarction within 3 months prior to screening
  • Transient ischemic attack or stroke within 3 months prior to screening
  • Uncontrolled hypertension (systolic 65180 or diastolic 65100 mm Hg) during screening
  • Use of pentoxifylline or cilostazol for claudication within 4 weeks prior to screening
  • Poorly controlled diabetes (HbA1c >12%)
  • Abnormal blood tests unsafe for exercise participation
  • Inability to speak English
  • Other significant unstable or confounding medical conditions as judged by the study team

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Minnesota

Minneapolis, Minnesota, United States, 55455

Actively Recruiting

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Research Team

C

Courtney Farland-Johnson, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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