Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06472206

Community Health Workers And MHealth to ImProve Viral Suppression Plus (CHAMPS+)

Led by Columbia University · Updated on 2025-07-04

420

Participants Needed

5

Research Sites

169 weeks

Total Duration

On this page

Sponsors

C

Columbia University

Lead Sponsor

U

University of Alabama at Birmingham

Collaborating Sponsor

AI-Summary

What this Trial Is About

Although global efforts have been made to end the HIV epidemic, there are still some gaps in HIV testing, antiretroviral therapy (ART) adherence, and viral suppression (VS) among people with HIV (PWH). These gaps are particularly prominent in the Deep South of the United States (US), where PWH face challenges in accessing healthcare services. In response, a team of experienced researchers has developed and tested the Community Health Workers And MHealth to ImProve Viral Suppression (CHAMPS) intervention. This intervention uses mobile health (mHealth) technology and a team of community health workers (CHW) to design an intervention to improve ART adherence and VS. The CHAMPS+ intervention adds a CHW delivered supportive risk reduction counseling during periods of non-suppression to prevent HIV transmission. The study will engage the participants by developing culturally relevant materials and retention strategies, evaluating the clinical effectiveness and sustainability of the intervention in Deep South settings, and assessing regionalized implementation factors. Ultimately, the study will test the effectiveness of CHAMPS+ on ART adherence and viral load suppression for PWH in Alabama, Louisiana, and Mississippi.

CONDITIONS

Official Title

Community Health Workers And MHealth to ImProve Viral Suppression Plus (CHAMPS+)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be able to speak, read, and write in English
  • Be above 18 years of age
  • Be willing to participate in any assigned arm of the intervention
  • Have an HIV-1 RNA level >200 copies/mL
  • Own a smartphone
  • Be able and willing to provide informed consent for study participation and consent for access to medical records
  • Live, work and/or receive care in Alabama, Louisiana, or Mississippi
Not Eligible

You will not qualify if you...

  • Reside in a nursing home, prison, or be receiving in-patient psychiatric care at time of enrollment
  • Have a terminal illness with life expectancy less than 6 months
  • Plan to move out of the area in the next 12 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

Health Services Center, Inc.

Hobson City, Alabama, United States, 36202

Actively Recruiting

2

Unity Wellness Center

Opelika, Alabama, United States, 36801

Actively Recruiting

3

Louisiana State University Health Sciences Center in New Orleans

New Orleans, Louisiana, United States, 70112

Actively Recruiting

4

Tulane University

New Orleans, Louisiana, United States, 70112

Actively Recruiting

5

University of Mississippi Medical Center

Jackson, Mississippi, United States, 39216

Actively Recruiting

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Research Team

R

Rebecca Schnall, PhD, MPH

CONTACT

M

Maeve Brin

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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