Actively Recruiting
Comparative Assessment of Lipid Layer Thickness Measurements Across Three Devices and Their Correlation With Clinical Indicators in Dry Eye Disease
Led by Indiana University · Updated on 2026-05-11
50
Participants Needed
1
Research Sites
N/A
Total Duration
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AI-Summary
What this Trial Is About
Researchers are evaluating the measurements of ocular lipid layer thickness (LLT) taken by three commonly used clinical devices to compare their agreement and consistency. The study also aims to find which device's LLT measurements best correlate with established clinical indicators of dry eye disease severity. Participants with dry eye disease will have their lipid layer thickness measured using three different devices: LipiView, Omnicad, and Bruder Ocular Surface Analyzer. These measurements will be taken during a single visit in a random order to ensure unbiased comparison. During the study visit, participants will undergo LLT measurement with all three devices. Researchers will analyze the measurements and compare them to clinical assessments of dry eye severity. The main outcome is the LLT measurement at baseline, alongside the correlation with clinical dry eye indicators. The study participation involves a single visit and does not include any treatment or long-term follow-up.
CONDITIONS
Brief Title
Comparative Assessment of Lipid Layer Thickness Measurements
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Dry eye disease
- Age between 18 and 100 years
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants with dry eye disease undergo lipid layer thickness measurements using three different devices in random order during a single visit.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Atwater Eye Care Center
Bloomington, Indiana, United States, 47405
Actively Recruiting
Research Team
A
Anna Tichenor
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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