Actively Recruiting
A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations
Led by Stanford University · Updated on 2025-04-24
400
Participants Needed
2
Research Sites
200 weeks
Total Duration
On this page
Sponsors
S
Stanford University
Lead Sponsor
P
Patient-Centered Outcomes Research Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is see if Cognitive Processing Therapy and STAIR Narrative Therapy work to treat posttraumatic stress disorder (PTSD) among lesbian, gay, bisexual, transgender, queer/questioning, intersex, asexual/aromantic, and all other sexual or gender minority (LGBTQIA+) adults. The main questions it aims to answer are: * Do these treatments reduce PTSD symptoms in LGBTQIA+ patients? * Do these treatments help improve quality of life and reduce depression in LGBTQIA+ patients? * Do stress from stigma and discrimination and drug/alcohol use change the impact of the treatment on PTSD symptoms? * Are LGBTQIA+ patients satisfied with these treatments? Do these treatments work differently among different groups within the LGBTQIA+ community? * Do LGBTQIA+ patients complete these treatments? Study participants will receive one of these two PTSD treatments. Participants will complete assessments before and after receiving treatment.
CONDITIONS
Official Title
A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Currently live in California
- Ability to understand study procedures and comply with them for the entire study
- Ability to understand and willing to sign a written informed consent document
- Ability to speak and read English or Spanish
- Identify as a sexual and/or gender minority
- Score 33 or higher on the PTSD Checklist-5 (PCL-5)
- Interest in getting treatment for PTSD
- Not currently in another psychotherapy treatment for PTSD (non-PTSD psychotherapy allowed)
- Able to attend in-person sessions in San Francisco or access treatment via videoconferencing
You will not qualify if you...
- Contraindication to any study-related procedure or assessment
- Clinically significant impairment interfering with study participation (e.g., schizophrenia, schizoaffective disorder, bipolar disorder)
- Active suicidal intent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Stanford University
Palo Alto, California, United States, 94304
Actively Recruiting
2
UCSF Alliance Health Project
San Francisco, California, United States, 94103
Actively Recruiting
Research Team
A
Annesa P Flentje, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here