A Comprehensive Review of Physical Therapy Interventions for Stroke Rehabilitation: Impairment-Based Approaches and Functional Goals.
Jawaria Shahid, Ayesha Kashif, Muhammad Kashif Shahid
https://pubmed.ncbi.nlm.nih.gov/37239189Actively Recruiting
Phase Not Applicable
Age: 45Years - 56Years
All Genders
ID07266662
Comparative Effects of Sensory Augmentation and Neuromodulation on Enhancing Motor Recovery Among Stroke Survivors
Led by Lahore University of Biological and Applied Sciences · Updated on 2025-12-17
36
Participants Needed
2
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of two rehabilitation techniques, Sensory Augmentation using mirror therapy and Neuromodulation using transcranial direct current stimulation (tDCS), on improving motor recovery in stroke survivors. The study focuses on adults aged 45 to 65 with chronic ischemic stroke affecting upper limb motor function. Stroke often causes long-term impairments that reduce independence, and this trial aims to identify more effective rehabilitation methods by comparing these innovative techniques alone and in combination with routine physical therapy. Participants will be randomly assigned to one of three groups: Group 1 receives a combination of mirror therapy and tDCS with routine physical therapy; Group 2 receives mirror therapy with routine physical therapy; and Group 3 receives tDCS with routine physical therapy. Treatments take place four times weekly for eight weeks. Each session lasts 45 minutes, with specific times dedicated to mirror therapy, tDCS, and physical therapy exercises focused on motor control and coordination. Throughout the study, participants will undergo assessments including the Fugl-Meyer Assessment and Jebsen-Taylor Test at baseline, 4 weeks, and 8 weeks to measure motor recovery and functional abilities. Additional evaluations will monitor quality of life, spasticity, handgrip strength, and sensory function. Safety is ensured by trained therapists, and all data will remain confidential. Participants may withdraw at any time without penalty, and the research aims to inform improved rehabilitation protocols for stroke survivors.
CONDITIONS
Brief Title
Comparative Effects of Sensory Augmentation and Neuromodulation on Enhancing Motor Recovery Among Stroke Survivors
Who Can Participate
Age: 45Years - 56Years
All Genders
Eligibility Criteria
You may qualify if you...
- Age between 45 and 65 years
- Both male and female participants
- Diagnosed ischemic stroke affecting the middle cerebral artery
- Chronic stage of recovery lasting more than 6 months
- Burnstromm recovery stage 3
- Good compliance with study procedures
You will not qualify if you...
- Vestibular dysfunction
- Serious cognitive impairment
- Severe vision problems or visuospatial neglect
- Spasticity with Modified Ashworth scale greater than 3
- Upper extremity contractures
- Upper extremity fractures
- Orthopedic diseases
- Neurological conditions other than stroke
- Recurrence of stroke or epilepsy during the study period
- Serious systemic impairments or concomitant diseases
- Refusal to participate in the experiment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - 8 weeks
Participants receive one of three interventions: a combination of Sensory Augmentation (Mirror Therapy) and Neuromodulation (tDCS) with Routine Physical Therapy; Sensory Augmentation with Routine Physical Therapy; or Neuromodulation with Routine Physical Therapy. These interventions aim to enhance motor recovery after stroke through sensory feedback, brain stimulation, and physical rehabilitation.
4 visits per week
Follow-up Assessments
Duration - 8 weeks concurrent with treatment
Participants undergo motor function and functional ability assessments to evaluate the effects of the interventions. These assessments include the Fugl-Meyer Assessment Scale and the Jebsen-Taylor Test conducted at baseline, 4 weeks, and 8 weeks.
3 assessment visits (baseline, Week 4, Week 8)
Trial Site Locations
Total: 2 locations
1
Lahore University of Biological and Applied Sciences
Lahore, Punjab Province, Pakistan
Not Yet Recruiting
2
Pakistan Society of Rehabilitation and Differently Abled Hospital
Lahore, Punjab Province, Pakistan
Actively Recruiting
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Research Team
S
Syed Asad Ali, Doctor of Physical Therapy
N
Nabeela Dawood, NMPT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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Jocelyn E Harris, Janice J Eng
https://pubmed.ncbi.nlm.nih.gov/17179441Spasticity, Motor Recovery, and Neural Plasticity after Stroke.
Sheng Li
https://pubmed.ncbi.nlm.nih.gov/28421032The definition of stroke.
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https://pubmed.ncbi.nlm.nih.gov/28084167