Actively Recruiting

Phase 2
Age: 1Year - 2Years
All Genders
NCT07451171

Comparative Efficacy of Antibiotics for Small Intestine Bacterial Overgrowth in Bangladeshi Children

Led by University of Virginia · Updated on 2026-05-06

60

Participants Needed

1

Research Sites

19 weeks

Total Duration

On this page

Sponsors

U

University of Virginia

Lead Sponsor

N

National Institutes of Health (NIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this Phase IIa study is to identify the most effective antibiotic regimen to treat small intestine bacterial overgrowth (SIBO) in impoverished Bangladeshi children.

CONDITIONS

Official Title

Comparative Efficacy of Antibiotics for Small Intestine Bacterial Overgrowth in Bangladeshi Children

Who Can Participate

Age: 1Year - 2Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Positive glucose hydrogen breath test (GHBT)
  • Weight-for-age Z score greater than -1
  • Length-for-age Z score greater than -1
Not Eligible

You will not qualify if you...

  • Known chronic or congenital illness, including developmental delay
  • Acute gastrointestinal illness within the past 14 days
  • Antibiotic use within the past 14 days
  • Previous adverse reaction to any of the study antibiotics or related drugs
  • Sibling previously enrolled in this study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b)

Dhaka, Bangladesh

Actively Recruiting

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Research Team

J

Jeffrey R Donowitz, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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