Comparing Hypertonic Saline and Adrenaline Nebulization Treatments for Acute Bronchiolitis in Children Aged 1 Month to 2 Years

What this Trial Is About

Researchers are evaluating the effectiveness of hypertonic saline nebulization compared to adrenaline nebulization for treating acute bronchiolitis in children aged between 1 month and 2 years. This study aims to assess improvement in the Wood-Downes clinical score, which evaluates respiratory symptoms, and the length of hospital stay for children with this condition. The study is a double-blind, randomized controlled trial conducted in a pediatric hospital setting. Children admitted with acute bronchiolitis will be randomly assigned to one of two groups. One group will receive nebulized hypertonic saline every 6 hours, where 0.3 ml of hypertonic saline is diluted with 3 ml of normal saline. The other group will receive nebulized adrenaline every 6 hours, prepared by diluting 0.3 ml adrenaline with 3 ml normal saline. Treatments are given over a period of 48 hours, with clinical assessments at 24 and 48 hours. Participants will be monitored for respiratory rate, heart rate, chest retractions, chest sounds, and oxygen levels to calculate the Wood-Downes-Ferres clinical score at 24 and 48 hours after treatment begins. Researchers will also record the length of hospital stay to evaluate treatment impact. Data collected will be analyzed for differences in clinical improvement and hospital stay duration. The total participation time varies depending on hospital stay length, with safety and effectiveness monitored throughout.

Comparative Efficacy of Hypertonic Saline vs Adrenaline Nebulization in Acute Bronchiolitis