Actively Recruiting

Phase 3
Age: 21Years - 80Years
All Genders
NCT07413055

Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial

Led by Oman Ministry of Health · Updated on 2026-03-30

138

Participants Needed

1

Research Sites

35 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to compare the effectiveness of 4mg and 8mg dexamethasone administered submucosally in reducing postoperative pain after dental implant surgery. Participants will be randomly assigned to receive either 4mg dexamethasone, 8mg dexamethasone, or a placebo (normal saline) at the surgical site. Later, postoperative pain will be assessed using a Visual Analog Scale at 6 hours after the surgery and daily for the next 6 days. Also the number of pain-relief tablets consumed after the surgery will be recorded. Preoperative anxiety will be assessed using Generalized Anxiety Disorder-7 (GAD-7) questionnaire to assess its association with postoperative pain scores. The results of this study will help determine the optimal dose of dexamethasone that is effective for postoperative pain control following dental implant surgery.

CONDITIONS

Official Title

Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial

Who Can Participate

Age: 21Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Males and females
  • Age between 21 and 80 years
  • ASA I or II classification according to American Society of Anesthesiologists
  • Scheduled for single tooth implant
  • Implant placement timing of type 3 or type 4 (Chen and Buser, 2009)
Not Eligible

You will not qualify if you...

  • Allergy to any medications used in the study
  • Current smoker or alcoholic
  • Pregnant or breastfeeding women
  • Need for bone augmentation or sinus lifting during surgery
  • Requirement for antibiotic prophylaxis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Al Nahdha Hospital

Muscat, Oman

Actively Recruiting

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Research Team

S

Shurooq Slim Al Hinai, BDS

CONTACT

N

Nasser Al Khaldi, Senior Consultant Prosth

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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