Comparing 4 mg and 8 mg Submucosal Dexamethasone for Pain Relief After Dental Implant Surgery A Randomized, Double-Blind Clinical Trial

What this Trial Is About

Researchers are evaluating the effect of two different doses of dexamethasone, 4mg and 8mg, given as a submucosal injection to reduce pain after dental implant surgery. The study is a randomized, double-blind, controlled clinical trial that also includes a placebo group receiving normal saline. The goal is to find the best dose of dexamethasone for managing postoperative pain while considering the influence of preoperative anxiety on pain levels. Participants will be randomly assigned to one of three groups receiving 8mg dexamethasone, 4mg dexamethasone mixed with saline, or a placebo injection of saline alone. Each injection is given near the surgical site in the buccal vestibule. The injections are concealed to ensure blinding. The study is planned to start in March 2026 and will follow participants for one week after surgery. During the study, postoperative pain will be measured using a Visual Analog Scale at 6 hours after surgery and daily for the next six days. The number of pain-relief tablets taken will also be recorded during this time. Preoperative anxiety levels will be assessed on the day of surgery using the Generalized Anxiety Disorder-7 questionnaire. The study will monitor these outcomes to determine the effectiveness of the dexamethasone doses in controlling pain after dental implant surgery.

Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial