Comparing Melatonin and Mineral Trioxide Aggregate for Vital Pulp Therapy in Childrens Young Permanent First Molars

What this Trial Is About

This research aims to evaluate and compare the pulp response in young permanent first molars after an apexogenesis procedure using melatonin versus mineral trioxide aggregate MTA. The study focuses on children aged 6 to 8 years with dental caries affecting these teeth, exploring whether melatonin, known for its role in bone growth regulation, has effects similar to MTA in vital pulp therapy. Participants will be divided into three groups of 15 teeth each one treated with MTA, another with melatonin powder mixed with saline, and the third with a mixture of MTA and melatonin powders. After the apexogenesis procedure, the selected material is placed as a sub base in the pulp chamber, followed by a permanent restoration using glass ionomer cement. Immediate postoperative digital x-rays will be taken, with follow-up visits scheduled at 1, 3, 6, 9, and 12 months to monitor progress. During the study, clinical assessments will include modified visual analogue scales, Millars index, and checks for presence or absence of symptoms, alongside radiographic evaluations using Image J software at all follow-up points. These evaluations will help measure the healing and response of the pulp to the treatments. The total participation duration is 12 months, with monitoring for any pulp healing, inflammation, and radiographic changes.

Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study