Actively Recruiting

Phase Not Applicable
Age: 6Years - 8Years
All Genders
Healthy Volunteers
NCT06372561

Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study

Led by Suez Canal University · Updated on 2024-08-02

45

Participants Needed

1

Research Sites

71 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The process of dental caries is dynamic and can be either reversible or irreversible depending on the balance between protective and pathologic factors in the oral cavity. Untreated dental caries causes pulpal injury, inflammation, and necrosis. Melatonin plays an essential role in the regulation of bone growth. The actions that melatonin exerts on odontoblasts may be similar to its action on osteoblasts.

CONDITIONS

Official Title

Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study

Who Can Participate

Age: 6Years - 8Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Children aged 6 to 8 years who are apparently healthy and medically free
  • Both boys and girls are included
  • Children must have mandibular permanent first molars that can be restored
  • No clinical signs of pulp degeneration, including no spontaneous or night pain, no pain on tapping, no tooth mobility
  • No abscess, purulent sinus, or soft tissue swelling
  • Bleeding from pulp should stop within 5 minutes after pulp amputation
Not Eligible

You will not qualify if you...

  • Internal root resorption
  • External root resorption
  • Bone destruction around or between roots seen on X-rays
  • Deep carious lesion close to the pulp seen on X-rays

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Faculty of Medicine, Suez canal university

Ismailia, Egypt, 41522

Actively Recruiting

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Research Team

M

Mennatallah Hesham El shaabany, doctorate student

CONTACT

A

Asmaa Ali Abo El-Soud, Associate professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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