Actively Recruiting
Comparative Imaging Assessment of Valvular Heart Disease
Led by The Cleveland Clinic · Updated on 2026-01-13
200
Participants Needed
1
Research Sites
436 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of the study is to compare the various 2D and 3D methods of valvular heart disease quantification (Doppler, PISA, VCA, volumetric method) and strain with cardiac magnetic resonance (CMR) measurements of left and right ventricular systolic function strain and myocardial fibrosis assessment.
CONDITIONS
Official Title
Comparative Imaging Assessment of Valvular Heart Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 90 years
- Suspected moderate or severe mitral regurgitation, aortic regurgitation, or aortic stenosis based on clinical history or exam
- Suspected cardiac resynchronization therapy non-responder with an implanted MRI-compatible device and reduced ejection fraction
You will not qualify if you...
- Acute traumatic cardiac injury
- Aortic dissection or aortic root rupture
- Congenital heart diseases such as patent ductus arteriosus, coarctation of aorta, atrial septal defect, or ventricular septal defect
- Presence of arteriovenous fistula or intracardiac shunts
- Any contraindications to cardiac magnetic resonance imaging
- Moderate or severe dysfunction in multiple heart valves
- Significant claustrophobia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Cleveland Clinic
Cleveland, Ohio, United States, 44195
Actively Recruiting
Research Team
D
Deborah Kwon, M. D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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