Actively Recruiting

All Genders
NCT06584097

COMparative Performance of General Purpose Models

Led by Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · Updated on 2026-02-12

42

Participants Needed

2

Research Sites

117 weeks

Total Duration

On this page

Sponsors

F

Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

Lead Sponsor

U

University Medical Center Groningen

Collaborating Sponsor

AI-Summary

What this Trial Is About

To compare the performance of the Eleveld models for propofol and remifentanil on neurosurgery patients admitted to intensive care with their intraoperative performance.

CONDITIONS

Official Title

COMparative Performance of General Purpose Models

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients undergoing elective neurosurgical procedures with an expected sedation after surgery of > 12 hours
  • Requirement for an arterial line
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Known sensitivity or allergy to propofol or remifentanil
  • Patient participating in research requiring exclusion due to other study protocols or health authority
  • Age under 18 years
  • Patients receiving propofol and/or remifentanil infusions not delivered through TCI pumps before inclusion
  • Patients exposed to other sedatives (benzodiazepines, volatile anesthetics, quetiapine) before inclusion

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Foundation IRCCS Carlo Besta Neurological Institute

Milan, Italy, Italy, 20133

Actively Recruiting

2

Fondazione IRCCS Istituto Neurologico C. Besta

Milan, Milano, Italy, 20133

Actively Recruiting

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Research Team

M

Michele Introna, M.D.

CONTACT

M

Marco Gemma, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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