Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
NCT05042687

Comparative Performance of Molecular Breast Imaging (MBI) to Magnetic Resonance Imaging (MRI) of the Breast in Identifying and Excluding Breast Carcinoma in Women at High Risk for Breast Cancer

Led by M.D. Anderson Cancer Center · Updated on 2026-04-15

300

Participants Needed

1

Research Sites

315 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To evaluate the diagnostic performance of Tc99m sestamibi (MBI) compared to breast MRI in women who are at high risk for developing breast cancer. To assess the relationship of tumor size, histologic subtype and location of lesion and how it affects lesion conspicuity and sensitivity in MBI detected cancers.

CONDITIONS

Official Title

Comparative Performance of Molecular Breast Imaging (MBI) to Magnetic Resonance Imaging (MRI) of the Breast in Identifying and Excluding Breast Carcinoma in Women at High Risk for Breast Cancer

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female patients aged 18 years and older of any race identified as having an elevated risk for breast cancer
  • High risk defined as lifetime risk over 20%, lobular neoplasia or atypical ductal hyperplasia, atypia NOS, or a genetic mutation predisposing to breast cancer
  • Scheduled for a Breast MRI and willing to complete both Breast MRI and MBI exams within a two-week window
  • Willing to undergo biopsy of any positive findings
  • Willing to complete a post-examination survey
  • Written informed consent obtained; language interpreter assistance provided for non-English speakers
Not Eligible

You will not qualify if you...

  • Pregnant women excluded due to use of radioactive tracer and gadolinium contrast in imaging exams

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

M D Anderson Cancer Center

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

B

Beatriz Adrada

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Comparative Performance of Molecular Breast Imaging (MBI) to Magnetic Resonance Imaging (MRI) of the Breast in Identifying and Excluding Breast Carcinoma in Women at High Risk for Breast Cancer | DecenTrialz