Actively Recruiting
Comparative Study Between HOMA1-IR and HOMA2-IR in Prediction of Ovulation Outcome in Women With PCOS
Led by Cairo University · Updated on 2025-02-05
122
Participants Needed
1
Research Sites
47 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
122 women diagnosed with PCOS seeking fertility in the fertility clinic at kasr Alainy hospital will be subjected to Homeostatic model assessment for insulin resistance 1 was calculated for all participants through the equation \[glucose (mmol/L) × insulin (µU/L)\]/22.5 while homeostatic model assessment for insulin resistance 2 was calculated by the HOMA2 calculator. All women will be subjected to induction of ovulation using the Aromatase inhibitor Letrozole 2.5 mg tab twice daily from the 3rd day of the cycle for 5 days . Ultrasound follow up of follicular growth will be performed till dominant follicular size reaches 18-22 mm. FSH preparations will be introduced as needed.
CONDITIONS
Official Title
Comparative Study Between HOMA1-IR and HOMA2-IR in Prediction of Ovulation Outcome in Women With PCOS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-35 years
- Duration of infertility 1-4 years
- Diagnosis of Polycystic Ovarian Syndrome (PCOS)
You will not qualify if you...
- Women with other causes of infertility such as tubal factor, uterine cavity abnormalities, or male factor
- Endometriosis
- Ovarian cysts
- Endocrinological abnormalities including diabetes mellitus, hypothalamic, pituitary, thyroid disorders, or hyperprolactinemia
- History of poor ovarian response or ovarian hyperstimulation
- Chronic diseases, chromosomal, autoimmune or coagulation defects, abnormal leucocytic count or other inflammatory markers
- Women with contraindications to pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Kasr Alainy medical school
Cairo, Egypt, 12111
Actively Recruiting
Research Team
A
Ahmed Maged, MD
CONTACT
A
Ahmed Chamel, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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