Actively Recruiting

Phase 2
Age: 18Years - 50Years
All Genders
NCT07472192

Comparative Study for Facial Scar Remodeling Using Fractional Carbon Dioxide Laser Combined With PDRN Versus Fractional CO₂ Laser

Led by Misr University for Science and Technology · Updated on 2026-03-16

36

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Facial scars are frequently deemed unpleasant and can profoundly impact a patient's psychological health. This study compares the effectiveness, safety, and capacity to speed up scar healing in the maxillofacial region between fractional carbon dioxide (CO₂) laser therapy alone and polydeoxyribonucleotide (PDRN) combined with CO₂ laser therapy.

CONDITIONS

Official Title

Comparative Study for Facial Scar Remodeling Using Fractional Carbon Dioxide Laser Combined With PDRN Versus Fractional CO₂ Laser

Who Can Participate

Age: 18Years - 50Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must be between 18 and 50 years of age
  • Facial wounds or surgical scars must be recent, about 1 to 6 months old
  • Willingness to provide informed consent and participate fully in the study
Not Eligible

You will not qualify if you...

  • Pregnant or breastfeeding at the time of study
  • Known allergy to polydeoxyribonucleotide (PDRN)
  • Use of medications that affect wound healing or inflammation such as isotretinoin, anticancer drugs, high-dose corticosteroids, or anticoagulants
  • Uncontrolled medical diseases like unstable diabetes or heart conditions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Misr University for Science and Technology

Giza, Egypt

Actively Recruiting

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Research Team

O

Omnia Tarek Hosni

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Comparative Study for Facial Scar Remodeling Using Fractional Carbon Dioxide Laser Combined With PDRN Versus Fractional CO₂ Laser | DecenTrialz