Actively Recruiting
Comparative Study: Fistula Rerouting vs. LIFT for High Perianal Fistula
Led by Cairo University · Updated on 2026-02-10
40
Participants Needed
1
Research Sites
39 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare two different surgery methods for treating a complex type of anal fistula. This condition is an abnormal tunnel connecting the inside of the anus to the skin nearby. The main questions the study aims to answer are: Which surgery has a lower chance of the fistula coming back (recurrence)? Which surgery has a lower chance of causing problems with bowel control (incontinence) after healing? Researchers will compare two surgery groups: Group 1: Fistula Rerouting Technique - a two-step surgery that moves the fistula tract to a safer area before opening it. Group 2: LIFT Technique - a surgery that ties off and closes the fistula tract from between the anal muscles. Participants will be randomly assigned by a computer to one of these two surgery groups. This helps ensure the comparison between the two surgeries is fair. Participants in this study will: * Have tests before surgery, including an MRI scan, to confirm they have the specific type of fistula being studied. * Undergo one of the two planned surgical procedures. * Attend follow-up visits after surgery at 1 week, 2 weeks, 1 month, and 3 months. * Be checked during these visits for wound healing, pain, infection, and bowel control. * Have another MRI scan if the fistula is suspected to have come back.
CONDITIONS
Official Title
Comparative Study: Fistula Rerouting vs. LIFT for High Perianal Fistula
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients aged 20 to 65 years with high perianal fistula, defined as trans-sphincteric fistula traversing the upper two-thirds of the external anal sphincter or extrasphincteric fistula
- Patients with recurrent perianal fistula
- Ability to provide informed consent
You will not qualify if you...
- Preoperative fecal incontinence as assessed by the Cleveland Clinic Fecal Incontinence Score
- Diagnosis of inflammatory bowel disease such as Crohn's disease or ulcerative colitis
- Pregnant women
- Pediatric patients under 20 years old
- Patients with complex, branching fistula tracts
- Contraindication to spinal or general anesthesia or surgery
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Faculty of Medicine Cairo University
Cairo, Al-Manial Cairo, Egypt, 11956
Actively Recruiting
Research Team
M
Mostafa Mohamed Sedky, Lecturer
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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