Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07346326

Comparative Study of Functional Outcomes Between Peroneus Longus and Hamstring Tendon Autografts in Arthroscopic ACL Reconstruction

Led by Khyber Medical University Peshawar · Updated on 2026-01-16

64

Participants Needed

1

Research Sites

36 weeks

Total Duration

On this page

Sponsors

K

Khyber Medical University Peshawar

Lead Sponsor

K

Khyber Medical College, Peshawar

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a prospective, single-blinded, randomized controlled trial. Sixty patients (≥18 years) with an isolated ACL injury will be randomly assigned to receive an ACL reconstruction using either a Peroneus Longus Tendon (PLT) autograft or a Hamstring Tendon (HST) autograft. The primary objective is to compare early functional outcomes between the two groups at 6 weeks and 3 months post-surgery, using the Lysholm Knee Score. The study aims to demonstrate the non-inferiority of the PLT graft. All surgeries will be performed arthroscopically at Khyber Teaching Hospital, Peshawar, followed by a standardized rehabilitation protocol.

CONDITIONS

Official Title

Comparative Study of Functional Outcomes Between Peroneus Longus and Hamstring Tendon Autografts in Arthroscopic ACL Reconstruction

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years or older.
  • Isolated, primary Anterior Cruciate Ligament (ACL) injury confirmed by clinical assessment and Magnetic Resonance Imaging (MRI).
  • Provides written informed consent for the surgical procedure and study participation, including follow-up assessments.
Not Eligible

You will not qualify if you...

  • Multiligament knee injuries (e.g., concomitant PCL, MCL, or LCL injuries).
  • Previous surgery or history of fracture in the involved lower limb.
  • Radiographic evidence of osteoarthritis in the affected knee.
  • Presence of any neuromuscular disease.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Khyber Teaching Hospital

Peshawar, KPK, Pakistan, 25100

Actively Recruiting

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Research Team

D

Dr Syed Dil Bagh Ali Shah, MBBS

CONTACT

D

Dr Syed Muhammad Shabbir Ali Naqvi, MSPT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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