Actively Recruiting

Phase 2
Phase 3
All Genders
NCT06496997

A Comparative Study of Glucocorticoids Efficacy in Acute Respiratory Distress Syndrome

Led by Fayoum University · Updated on 2025-01-06

300

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of the work is to compare the efficacy of equivalent doses of methylprednisolone, dexamethasone and hydrocortisone in patients with ARDS

CONDITIONS

Official Title

A Comparative Study of Glucocorticoids Efficacy in Acute Respiratory Distress Syndrome

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Receiving mechanical ventilation for hypoxemic respiratory failure
  • Diagnosed with ARDS based on the American-European Consensus and 2012 Berlin criteria
  • Acute hypoxemic respiratory failure with PaO2/FiO2 ratio of 300 mm Hg or less
  • Requires supplemental oxygen to keep oxygen saturation above 93% within 48 hours of ARDS onset
  • Respiratory symptoms started or worsened within 7 days
  • Bilateral opacities on chest x-ray or CT not explained by other lung conditions
  • Cardiac failure not the primary cause of respiratory failure
Not Eligible

You will not qualify if you...

  • Acute hypoxemic respiratory failure caused by congestive heart failure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fayoum University

Al Fayyum, Egypt

Actively Recruiting

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Research Team

M

Mahmoud Ezzat Elkmash, Teaching assistant

CONTACT

M

Marwa Kamal Tolba, Assistant Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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