Actively Recruiting
Comparative Study of New Classification and Traditional Classification of Radioactive Oropharyngeal Mucositis
Led by Nanfang Hospital, Southern Medical University · Updated on 2025-07-16
264
Participants Needed
4
Research Sites
65 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Radiation oropharyngeal mucositis is one of the most painful side effects of radiotherapy in patients with head and neck tumors. However, the traditional radioactive oropharyngeal mucositis grading system has the problem of poor evaluation consistency. To solve this problem, we innovatively classify radiation oropharyngeal mucositis into four types according to the four-stage histopathological changes of acute radiation injury: (1) congestive; (2) Scattered erosion type; (3) Fusion erosion type; (4) Ulcer type. We intend to conduct a multicenter observational cohort study to compare the consistency of different physicians in the assessment of radiation oropharyngeal mucositis with new and traditional classifications, and to explore changes in blood markers of different types of oropharyngeal mucositis using clinical residual blood samples.
CONDITIONS
Official Title
Comparative Study of New Classification and Traditional Classification of Radioactive Oropharyngeal Mucositis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Voluntarily sign informed consent
- Age 18 or older on the date of signing the informed consent
- Histologically confirmed head and neck tumor
- Undergoing radiotherapy or chemoradiotherapy
You will not qualify if you...
- Presence of uncontrolled serious medical conditions such as unstable heart disease requiring treatment
- Poorly controlled diabetes with fasting blood glucose greater than 1.5 times the upper limit of normal
- Mental illness
- History of severe allergies
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 4 locations
1
Southern medical university
Guangzhou, Guangdong, China, 510515
Actively Recruiting
2
Huizhou Central People's Hospital
Huizhou, Guangdong, China, 516000
Not Yet Recruiting
3
Jieyang people's hospital
Jieyang, Guangdong, China, 522000
Not Yet Recruiting
4
Meizhou People's Hospital, Meizhou Academy of Medical Sciences Meizhou
Meizhou, Guangdong, China, 514000
Not Yet Recruiting
Research Team
J
Jian Guan, M.D
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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