Actively Recruiting

Age: 18Years - 75Years
All Genders
NCT05738525

Comparative Study of Prognosis and QOL Between APD-RPM and CAPD

Led by Chinese PLA General Hospital · Updated on 2023-06-22

750

Participants Needed

1

Research Sites

182 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is an observational, multicenter, parallel control study, planning to enroll 750 eligible patients to receive automated peritoneal dialysis with remote patient management (APD-RPM) and continuous ambulatory peritoneal dialysis (CAPD). Patients will attend follow-up every 12 ± 1 weeks for a total of 156 weeks. This study aims to compare the effects of APD-RPM and CAPD treatment on the prognosis and quality of life.

CONDITIONS

Official Title

Comparative Study of Prognosis and QOL Between APD-RPM and CAPD

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18 years to 75 years
  • Confirmed diagnosis of end-stage renal disease
  • Rapid peritoneal solute transfer rate shown by 4-hour D/P creatinine value greater than 0.65
  • Able to comply with standard peritoneal dialysis treatment at home
  • On peritoneal dialysis for 3 months or longer
  • Fully understand the study and have signed informed consent
Not Eligible

You will not qualify if you...

  • Preparing for kidney transplantation within 3 years
  • Need combined hemodialysis treatment
  • Allergic to components of peritoneal dialysis fluid
  • Severe cardio-cerebrovascular diseases, including congestive heart failure grade III or above, recent heart attack or stroke, malignant arrhythmia needing treatment, dilated cardiomyopathy
  • Serious liver diseases such as cirrhosis or acute liver injury with ALT or AST twice the normal level
  • Active or treated malignant tumors, HIV infection
  • Pregnant or breastfeeding women who do not agree to use effective contraceptives during the trial
  • History of alcohol or illegal drug abuse
  • Unable to continue CAPD due to ultrafiltration failure
  • Mental retardation or mental illness
  • Use of icodextrin dialysate
  • Participation in other clinical trials in past 3 months
  • Peritonitis in past 3 months
  • Other conditions as decided by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Chinese PLA General Hospital

Beijing, Beijing Municipality, China, 100853

Actively Recruiting

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Research Team

X

Xiangmei Chen

CONTACT

J

Jianhui Zhou

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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