Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06440759

To Compare the Efficacy and Safety of Using oXiris and M100 During CRRT

Led by Mohd Zulfakar Mazlan, MBBS · Updated on 2025-10-02

60

Participants Needed

1

Research Sites

100 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study aimed to compare the efficacy of Oxiris (Baxter) and M100 filters on IL-6 as primary outcomes and other blood cell counts, blood biochemistry (serum urea, creatinine, potassium, sodium), inflammation indicators (CRP, PCT), as secondary outcomes and safety (28 days mortality as a primary outcome and coagulopathy, lifespan of filter, usage of vasopressor, clinical conditions (ventilator-free days, ICU and hospital- length of stay) as a secondary outcome), clinical conditions (ventilator-free days, ICU and hospital- length of stay), and mortality of patients with pneumonia-related AKI.

CONDITIONS

Official Title

To Compare the Efficacy and Safety of Using oXiris and M100 During CRRT

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients aged over 18 years
  • Diagnosis of septic shock
  • Diagnosis of KDIGO stage 3 acute renal failure
Not Eligible

You will not qualify if you...

  • Moribund patients or those expected to die within 72 hours
  • Pregnancy
  • Patients with bleeding tendency or known allergy to heparin

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital Universiti Sains Malaysia (HUSM)

Kubang Kerian, Kelantan, Malaysia, 16150

Actively Recruiting

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Research Team

M

Marina Azidah Mat Zaid, MBBS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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