Actively Recruiting
To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.
Led by University of Alabama at Birmingham · Updated on 2026-03-20
40
Participants Needed
1
Research Sites
143 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will compare commercially available, commonly used mouth rinses (0.12% chlorhexidine (CHX) vs. Ethylenediaminetetraacetic acid (EDTA)) for immediate post-operative and daily antiseptic use after tooth extraction and ridge preservation grafting followed by daily use of commercially available an essential oil (EO) mouthrinse and EDTA mouthrinse.
CONDITIONS
Official Title
To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to read and provide informed consent in English
- At least 18 years old
- Established and registered patient of the UAB School of Dentistry
- Patients with one single-rooted tooth needing extraction and ridge preservation bone grafting for future dental implant placement
- Presence of periodontally healthy, non-carious neighboring teeth and/or healthy restored dental implants on either side of the tooth planned for extraction
- No planned surgical or endodontic treatment on teeth adjacent to the surgical site during the study period
You will not qualify if you...
- Non-English speaking
- Younger than 18 years old or older than 85 years old
- Smokers or nicotine users exceeding 10 cigarettes or equivalent per day
- Patients with systemic diseases or conditions that contraindicate oral surgery or impair wound healing
- Multiple adjacent teeth needing extraction and grafting
- Absence of adjacent teeth or implants on either side of the tooth to be extracted
- Known or suspected allergy or sensitivity to any study product
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294-0007
Actively Recruiting
Research Team
M
Maria L Geisinger, DDS, MS
CONTACT
S
Sarah Jane Startley, DMD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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