Actively Recruiting
Comparing Antipsychotic Medications in LBD Over Time
Led by The University of Texas Health Science Center at San Antonio · Updated on 2025-09-09
94
Participants Needed
2
Research Sites
249 weeks
Total Duration
On this page
Sponsors
T
The University of Texas Health Science Center at San Antonio
Lead Sponsor
A
Alzheimer's Association
Collaborating Sponsor
AI-Summary
What this Trial Is About
The primary objective of this study is to determine whether treatment with pimavanserin or quetiapine is associated with a greater improvement in psychosis when used in a routine clinical setting to treat hallucinations and/or delusions due to Parkinson's disease (PD) or dementia with Lewy bodies (DLB) - collectively referred to as Lewy body disease (LBD).
CONDITIONS
Official Title
Comparing Antipsychotic Medications in LBD Over Time
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients seen in the neurology clinic at UT Health San Antonio
- Diagnosed with psychosis due to Parkinson's disease or dementia with Lewy bodies
- Requiring initiation of an antipsychotic medication
- Clinical equipoise between quetiapine and pimavanserin must exist
- The prescribing provider must be comfortable prescribing and managing both quetiapine and pimavanserin
You will not qualify if you...
- Medical contraindication to either medication
- Caregiver unavailable to complete Neuropsychiatry Inventory Questionnaire
- Currently taking an antipsychotic medication
- Prescribing provider unwilling to manage either medication
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University Health System
San Antonio, Texas, United States, 78229
Actively Recruiting
2
UT Health Science Center - San Antonio
San Antonio, Texas, United States, 78229
Actively Recruiting
Research Team
C
Carolyn Paiz, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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