Actively Recruiting
Efficacy of Ultrasound Guided Pectoral Nerve Block Versus Ultrasound Guided Mid-point Transverse Process Block for Postoperative Analgesia in Patients Undergoing Modified Radical Mastectomy
Led by Ain Shams University · Updated on 2025-03-13
60
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to compare the effectiveness of two ultrasound-guided nerve block methods—pectoralis nerve block and mid-point transverse process block—for managing pain after modified radical mastectomy in female patients aged 35 to 65 years. The study evaluates which method provides better postoperative pain relief and measures the time until patients first request additional pain medication. Patients will be randomly assigned to one of two groups after induction of general anesthesia. The pectoral nerve block group will receive 10ml of bupivacaine 0.5% between the pectoralis major and minor muscles, followed by another 10ml between the pectoralis minor and serratus anterior muscles. The mid-point transverse process block group will receive 20ml of bupivacaine 0.5% near the T4 vertebra, injected between the transverse process and the pleura. Both procedures are performed by an experienced anesthesiologist using ultrasound guidance under sterile conditions. Participants will be monitored during surgery with standard anesthesia care and vital sign recording. Pain levels will be assessed using a numeric rating scale, and the primary outcome is the time until the first request for additional pain relief over 18 hours after surgery. Secondary outcomes include the number of patients needing rescue analgesia, total doses used, and any complications within 18 hours postoperatively. The study will also track dosing of anesthesia and pain medications during the operation and after skin closure.
CONDITIONS
Brief Title
Comparing Between Ultrasound Guided Pectoral Nerve Block Versus Ultrasound Guided Mid-point Transverse Process Block for Postoperative Analgesia in Patients Undergoing Modified Radical Mastectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female patients undergoing modified radical mastectomy
- Age between 35 and 65 years
You will not qualify if you...
- Patient refusal of procedure or participation in the study
- Operation duration longer than 180 minutes
- Known ASA physical status IV or higher
- Local skin infection at the block site
- Contraindications to local anesthetic infiltration such as coagulopathy, use of anticoagulant or antiplatelet therapy, or known allergy to bupivacaine
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Surgery duration up to 3 hours
Participants undergo general anesthesia followed by one of two ultrasound-guided nerve block procedures for postoperative pain relief during modified radical mastectomy surgery.
1 visit (in-person) on the day of surgery
Duration - Up to 18 hours after surgery
Participants are monitored for pain and use of rescue analgesia for up to 18 hours after surgery.
Approximately 1 follow-up period up to 18 hours post-surgery
Trial Site Locations
Total: 1 location
1
Ainshams university
Cairo , Abbassya, Egypt
Actively Recruiting
Research Team
Y
yasmin tarek elshahawy, assistant lecturer
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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