Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06870799

Comparing Closed Face Masks vs Surface Guided Radiation Therapy for Head and Neck Radiotherapy

Led by University of Zurich · Updated on 2025-05-18

25

Participants Needed

1

Research Sites

102 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

At present, open-face masks are used only in patients with claustrophobic anxiety, while all other patients are still immobilized with closed masks, thereby overlooking the need for improvement in patient comfort. Closed face masks in patients undergoing head and neck irradiation have never been compared to no masks in the setting of a randomized clinical trial, but only in feasibility trials. A randomized clinical trial may establish the role of no masks in terms of patient comfort, preference and setup accuracy in all patients.

CONDITIONS

Official Title

Comparing Closed Face Masks vs Surface Guided Radiation Therapy for Head and Neck Radiotherapy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Provide written informed consent according to Swiss law and ICH/GCP regulations before any trial procedures
  • Have an indication for head and neck radiotherapy regardless of tumor type
  • Be 18 years of age or older
  • Have a Karnofsky performance status of 70 or higher
  • Be willing and able to comply with scheduled visits, treatment, and trial procedures
Not Eligible

You will not qualify if you...

  • Previous head and neck radiotherapy
  • Women who are pregnant or breastfeeding
  • Planning to become pregnant during the trial
  • Lack of safe contraception for women of childbearing potential during the study
  • Known or suspected drug or alcohol abuse or non-compliance
  • Inability to follow trial procedures, including language barriers
  • Investigator, their family members, employees, or dependent persons involved in the trial
  • Tumor types of nasopharynx or sinunasal, or clinical target volume within 5 mm of eyes or spinal cord

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital Zurich

Zurich, Switzerland, 8091

Actively Recruiting

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Research Team

K

Katerina Nilo

CONTACT

C

Crystal Sulaiman

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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