Comparing Different Sized Flexible Ureteroscopes with Similar Ureteral Access Sheaths for Treating Upper Urinary Tract Stones - A Randomized Multi-center Clinical Trial

What this Trial Is About

Researchers are evaluating and comparing the efficiency, effectiveness, and safety of flexible ureteroscope fURS lithotripsy using similar ureteral access sheaths RESDs for treating upper urinary tract stones. The study focuses on patients with kidney or upper ureteral stones less than 3 cm in total size and aims to assess different diameter flexible ureteroscopes combined with access sheaths to improve surgical outcomes. The study compares two groups one uses a 7.5Fr disposable electronic flexible ureteroscope combined with a 10Fr deflectable ureteral access sheath, and the other uses a 9.0Fr disposable electronic flexible ureteroscope combined with a 12Fr access sheath. Both groups receive ureteral soft lens holmium laser lithotripsy. This is a randomized, single-masked, multi-center clinical trial conducted by Ningbo No. 1 Hospital. Participants will be monitored from enrollment through surgery completion to measure the success rate of ureteral access sheath insertion. Additional assessments include ureter injury condition within 24 hours, stone clearance rate up to 8 weeks post-surgery, operation time within 24 hours, and surgical complications within 7 days. The total study duration for each participant includes these follow-up periods to ensure comprehensive safety and effectiveness evaluations.

Comparing Different Diameter fURSs With Similar RESDs for the Treatment of Upper Urinary Tract Stones